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Possible with high doses or excessive frequency: Downregulation Chronic high exposure reduction LHCGR expression Prevention Physiological doses (500-1500 IU 2-3x/week) Signs Decreased testosterone response, requires increasing doses Recovery Rest 4-8 weeks to restore sensitivity Main side effects research

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A: SHAM group, strong in myofibers and endothelium

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Attempts to improve stress resistance have therefore consisted in overexpressing certain types of enzymes, for example those involved in the synthesis of osmoprotectors [xx]